Endocrine Abstracts

IntroductionSome, cases of autoimmune diseases were previously reported after surgical remission of CD. In most cases, autoimmune diseases have generally been reported in younger females. However, some cases of Hashimoto’s thyroiditis, multiple sclerosis, vitiligo, and sarcoidosis in male patients, after the restoration of hypercortisolemia have been reported as well. Nevertheless, an immediate occurrence of severe erosive rheumatoid arthritis (RA) ...

IntroductionMulticentric Castleman disease (MCD) is characterized by highly vascularized multiple lymph node enlargements throughout the body. MCD is generally treated with systemic cytotoxic chemotherapy, with its attendant risk for toxicity. Studies suggest the presence of growth hormone receptors (GHR) in lymphatic tissues of patients with Castleman disease. However, the effect of somatostatin analogs for the treatment of MCD is not reported so far. H...

IntroductionThe diagnosis of insulinomas is made biochemically. However, proper localization of insulinomas is essential before surgery. Non-invasive methods including magnetic resonance imaging (MRI), computed tomography, ultrasonography, glucagon-like peptide-1 receptor PET/CT, 68Ga-DOTATATE PET/CT, and invasive methods such as endoscopic ultrasonography (EUS) and selective arterial calcium stimulation test are used for preoperative localization. Howev...

IntroductıonRecent studies suggest temozolomide as an effective treatment modality in invasive pituitary adenomas that did not respond to conventional treatments. In this case series, we present three cases of invasive pituitary adenomas that did not respond to conventional medical treatments and radiotherapy and were subsequently treated with temozolomide.CasesThe first patient had an invasive prolactin...

Introduction: Dabigatran is a direct thrombin inhibitor which is used for reducing the risk of stroke or systemic embolism in patients with atrial fibrillation. Although INR monitoring is not required in the course of treatment, it may be complicated with spontaneous systemic bleeding. Sheehan’s syndrome is characterized with panhypopituitarism which is caused by necrosis of the pituitary gland. Recent studies have demonstrated that panhypopituitarism is associated with b...